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The global monocyte activation test market is witnessing continuous advancements in test offerings and extensive growth in the product portfolio of major as well as local manufacturers. The growth of the global monocyte activation test market is attributed to increasing number of pharmaceutical and biotechnology industries globally, rising research and development, increased investments and surge in new drug approval activities. Additionally, a proposed ban on animal tests has resulted in reducing the use of the rabbit for pyrogen test. This is one of the significant factors that is driving the growth of monocyte activation tests globally. Increase in public and regulatory concerns about product safety further support the market growth. Major Key Players of the Monocyte Activation Test Market are: Merck, Thermo Fisher Scientific, Becton, Dickinson and Company, Sanquin, Charles River Laboratories International, Inc., Microcoat Biotechnologie GmbH, SOLVIAS AG and Lonza Group among others...

Monocyte activation test is one of the tests or examinations for the detection of pyrogens. A pyrogen is an element or the substance that creates rise in temperature in animal or in human. Pyrogens include heterogeneous class of fever with compounds obtained from microorganisms and the non-microbial elements. This type of pollution is called as a severe public health issue and can lead to symptoms from vascular modifications to death and shock. The MAT testing is essential for ensuring the optimal safety of the parenteral pharmaceutical products as well as the medical devices. The MAT test or the monocyte activation test is capable enough to detect both non-endotoxin and endotoxin pyrogens in one single test. Backed by several regulatory bodies, this strong MAT test assay generates sensitive results depending on the human immune reaction. Monocyte Activation Test market was valued at over US$ 6.5 Mn. in 2018 and is anticipated to grow at a CAGR of 12.5% from 2019 to 2030. The globa...

Monocyte Activation Test market was valued at over US$ 6.5 Mn. in 2018 and is anticipated to grow at a CAGR of 12.5% from 2019 to 2030. The global monocyte activation test market is witnessing continuous advancements in test offerings and extensive growth in the product portfolio of major as well as local manufacturers. The growth of the global monocyte activation test market is attributed to increasing number of pharmaceutical and biotechnology industries globally, rising research and development, increased investments and surge in new drug approval activities. Additionally, a proposed ban on animal tests has resulted in reducing the use of the rabbit for pyrogen test. This is one of the significant factors that is driving the growth of monocyte activation tests globally. Increase in public and regulatory concerns about product safety further support the market growth. Major Key Players of the Monocyte Activation Test Market are: Merck, Thermo Fisher Scientific, Becton, Dickinson ...

Monocyte Activation Test market was valued at over US$ 6.5 Mn. in 2018 and is anticipated to grow at a CAGR of 12.5% from 2019 to 2030. The global monocyte activation test market is witnessing continuous advancements in test offerings and extensive growth in the product portfolio of major as well as local manufacturers. The growth of the global monocyte activation test market is attributed to increasing number of pharmaceutical and biotechnology industries globally, rising research and development, increased investments and surge in new drug approval activities. Additionally, a proposed ban on animal tests has resulted in reducing the use of the rabbit for pyrogen test. This is one of the significant factors that is driving the growth of monocyte activation tests globally. Increase in public and regulatory concerns about product safety further support the market growth. Major Key Players of the Monocyte Activation Test Market are: Merck, Thermo Fisher Scientific, Becton, Dickinson ...

Animals are used to test both the safety and efficacy of therapeutic drugs, cosmetics, household products, and chemicals. Fortunately there are developing numbers of effective non-animal alternatives that can replace the use of animals in pyrogen testing. Moreover, many countries have regulatory requirements that stipulate a ban on animal based pyrogen testing. There have been major changes in the European Union in recent years. In the EU the use of animals for pyrogen testing of cosmetic products has been banned since 2009, the use of animals for the testing of cosmetic ingredients also has been banned since March 2013. Furthermore, the EU banned the sale of any cosmetics tested on animals from March 2013 onwards. Israel imposed similar cosmetic testing bans in 2007 and 2013, and similar policy change is under consideration in India and South Korea. These factors are anticipated to present a lucrative growth opportunity for the global monocyte activation test market in the coming year...

  A report "Monocyte Activation Test (MAT)" has been recently published by Market Industry Reports (MIR). As per the published report, the global monocyte activation test market was estimated to be over US$ 6.63 million in 2018. It is anticipated to grow at a CAGR of 13.3% from 2019 to 2030. The global  monocyte activation test market  is witnessing continuous advancements in test offerings and extensive growth in the product portfolio of major as well as local manufacturers. The growth of the global monocyte activation test market is attributed to increasing number of pharmaceutical and biotechnology industries globally, rising research and development, increased investments and surge in new drug approval activities. Additionally, a proposed ban on animal tests has resulted in reducing the use of the rabbit for pyrogen test. This is one of the significant factors that is driving the growth of monocyte activation tests globally. Increase in public and regulatory concerns ...

Monocyte activation testing is the test that detects the presence of pyrogens (an element produced by bacterium that triggers fever in the body) in pharmaceutical products and all the medical devices. Pryogens are the harmful substances derived from microorganisms, inducing fever in animals and humans. When a pryogen enters in a bloodstream, it induces natural immunity that causes fever due to cytokines.  Monocyte activation test (MAT)  is capable of identifying endotoxin and non-endotoxin pyrogens, both in one single test. This test is supported by several regulatory bodies, and the MAT itself is strong enough to generate sensitive results dependent on human immune reaction. The growing pandemic of corona virus has significantly impacted the extensive use of monocyte activation test. The rising number of positive cases of corona virus, across the globe gave rise to the use of this testing. Owing to the ability of recognizing and potential of the test to detect early symptoms...

Monocyte activation test market was estimated to be over US$ 6.63 million in 2018. It is anticipated to grow at a CAGR of 13.3% from 2019 to 2030. There are several advantages of monocyte activation test which increases its application over the other pyrogen testing available. The advantages of MAT includes high efficiency of detection of both endotoxin & non-endotoxin contaminants, accurate analyses of pyrogenic activity in complex pharmaceuticals such as blood-derived products, cell-derived products, biologics and vaccines. Moreover, the shift in regulatory approvals in several regions is favouring the adoption of monocyte activation test over animal based tests such as Rabbit Pyrogen test (RPT). For instance, in the year 2010, a chapter on MAT was introduced in the European Pharmacopeia as an alternative to the Rabbit Pyrogen test wherever possible. Similarly, in Japan, a general notice was included in the JP XVII edition, which indicated the application of MAT for diagnostic p...

Market Industry Reports (MIR) has published a new report titled "Monocyte Activation Test Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2019-2030." The global Monocyte Activation Test market was valued at over US$ 6.5 Mn. in 2018 and is anticipated to grow at a CAGR of 12.5% from 2019 to 2030. Monocyte activation test based on the reaction of human monocytes, now allows predicting the human response to all pyrogens (i.e. endotoxin and non-endotoxin) in vitro. The MAT can be used as alternative to animal-based pyrogen testing. The MAT is used to detect or quantify substances that activate human monocytes or monocyte cells to release endogenous mediators which have a role in the human fever response. The MAT offers significant advantages over animal-based pyrogen testing: based on the human fever response, it provides a more relevant prediction of pyrogenic activity than the rabbit pyrogen test (RPT), it can detect endotoxin and non-endotoxin py...