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Next generation sequencing (NGS) also known as high-throughput sequencing enables scientists to sequence and assemble billions of short DNA reads. The advent of next generation sequencing technologies has brought significant changes in the sequencing process by providing high throughput, speed, flexibility and reduced sequencing cost over thousand folds. NGS has ability to generate hundreds of gigabases of nucleotide sequence data in a single sequencing run. The technology is emerging at a rapid rate due to its growing adoption in clinical applications as it allows scanning of whole genomes or targeted genomes in less span of time. In addition, reduction in cost of sequencing has also expanded the usage of next generation sequencing in variety of clinical applications. The technique has imparted its usage in various clinical applications such as cancer, inherited genetic disorders, HLA typing and identification of infectious diseases. For instance, NGS has been used for tracing hospi...

Next-generation sequencing is the process of sequencing DNA strands similar to the nucleotides in a DNA molecule. Next-generation sequencing is carried by massive parallelization. Next-generation sequencing reduces the requirements for the fragment-cloning method used in sequencing of the genomes by Sanger’s method. Due to high accuracy, precise results, and low cost, and with low sample, next-generation sequencing is preferred over the Sanger’s method. It is commonly used in oncology studies, biomarker discovery, agricultural and animal research, personalized medicine, and others. In addition, re-sequencing of targets, identification of binding sites of a transcriptional factor, and non-coding RNA expression profiling are other applications of next-generation sequencing. Some of the players in global next-generation sequencing market are: Agilent Technologies, Inc. (U.S.), Illumina, Inc. (U.S.), Pacific Biosciences (Danaher Corporation) (U.S.), Thermo Fisher Scientific Inc. (U.S.), Qi...

Next-generation sequencing is the process of sequencing DNA strands similar to the nucleotides in a DNA molecule. Next-generation sequencing is carried by massive parallelization. Next-generation sequencing reduces the requirements for the fragment-cloning method used in sequencing of the genomes by Sanger’s method. Due to high accuracy, precise results, and low cost, and with low sample, next-generation sequencing is preferred over the Sanger’s method. It is commonly used in oncology studies, biomarker discovery, agricultural and animal research, personalized medicine, and others. In addition, re-sequencing of targets, identification of binding sites of a transcriptional factor, and non-coding RNA expression profiling are other applications of next-generation sequencing. Some of the players in global next-generation sequencing market are: Agilent Technologies, Inc. (U.S.), Illumina, Inc. (U.S.), Pacific Biosciences (Danaher Corporation) (U.S.), Thermo Fisher Scientific Inc. (U.S.), Qi...